PDF-ikonPrintikon

Publications

Peer-reviewed publications

H-index: 14; Total number of citations: 1.049 (August 2014)

25. Storry JR, Condon J, Hult AK, Harrison A, Jørgensen R, Olsson ML. An Age-dependent ABO Discrepancy Between Mother And Baby Reveals A Novel Aweak Allele. Transfusion. 2014 (Accepted for publication July 24, 2014) PubMed

24. Welner D, Dedic E, van Leeuwen HC, Kuijper E, Bjerrum MJ, Østergaard O, Jørgensen R. Protein expression, characterization, crystallization and preliminary X-ray crystallographic analysis of a Fic protein from Clostridium difficile. Acta Cryst F Struct Biol Commun. 2014; 70(Pt 6), 827-831 PubMed

23. Jørgensen R, Batot G, Mannerstedt K, Imberty A, Breton C, Hindsgaul O, Royant A, Palcic MM. Structures of a human blood group glycosyltransferase in complex with a photo-activatable UDP-Gal derivative reveal two different binding conformations. Acta Cryst F Struct Biol Commun. 2014; 70(Pt 8), 1015-1021 PubMed 

22. Hoover GJ, Jørgensen R (co 1st author), Rochon A, Bajwa VS, Merrill AR, Shelp BJ. Identification of catalytically important amino acid residues for enzymatic reduction of glyoxylate in plants. Biochim Biophys Acta. 2013; 1834(12), 2663-2671 PubMed

21. Jørgensen R (co-corresponding author), Pesnot T, Lee HJ, Palcic MM, Wagner GK. Base-modified donor analogues reveal novel dynamic features of a glycosyltransferase. J Biol Chem. 2013; 288(36), 26201-26208 PubMed

20. Svensson L, Hult AK, Stamps R, Ångström J, Teneberg S, Storry JR, Jørgensen R, Rydberg L, Henry SM, Olsson ML. Forssman expression on human erythrocytes: biochemical and genetic evidence of a new histo-blood group system. Blood. 2013; 121(8), 1459-1468 PubMed 

Blood

Selected for the front cover of this journal issue.

19. Fieldhouse RJ, Jørgensen R, Lugo MR, Merrill AR. The 1.8 angstrom cholix toxin crystal structure in complex with NAD and evidence for a new kinetic model. J Biol Chem. 2012; 287(25), 21176-21188 PubMed

18. Jørgensen R, Grimm LL, Sindhuwinata N, Peters T, Palcic MM. A glycosyltransferase inhibitor from a molecular fragment library simultaneously interferes with metal ion and substrate binding. Angew Chem Int Ed Engl. 2012; 51(17), 4171-4175 PubMed 

17. Turgeon Z, Jørgensen R (co 1st author), Visschedyk D, Edwards PR, Legree S, McGregor C, Fieldhouse RJ, Mangroo D, Schapira M, Merrill AR. Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins. Antimicrob Agents Chemother. 2011; 55(3), 983-991 PubMed 

16. Pesnot T, Jørgensen R (co 1st author), Palcic MM, Wagner GK. Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat Chem Biol. 2010; 6(5), 321-323. Featured in Chemical & Engineering News (19 April 2010 issue, p34), Science Daily (5 April 2010), The Daily Express (5 April, 2010), The Daily Mirror (5 April 2010), The Daily Telegraph (4 April 2010), Eastern Daily Press (4 April 2010) PubMed 

15. Hult AK, Yazer MH, Jørgensen R, Hellberg A, Hustinx H, Peyrard T, Palcic MM, Olsson ML. Weak A phenotypes associated with novel ABO alleles carrying the A2-related 1061C deletion and various missense substitutions. Transfusion. 2010; 50(7), 1471-1486 PubMed

Transfusion

Selected for the front cover of this 50-year anniversary journal issue.

 14. Turgeon Z, White D, Jørgensen R, Visschedyk D, Fieldhouse RJ, Mangroo D, Merrill AR. Yeast as a tool for characterizing mono-ADP-ribosyltransferase toxins. FEMS Microbiol Lett. 2009; 300(1), 97-106 PubMed

13. Jørgensen R, Wang Y, Visschedyk D, Merrill AR. The nature and character of the transition state for the ADP-ribosyltransferase reaction. EMBO Rep. 2008; 9(8), 802-809 PubMed

12. Jørgensen R, Purdy AE, Fieldhouse RJ, Kimber MS, Bartlett DH, Merrill AR. Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae. J Biol Chem. 2008; 283(16), 10671-10678 PubMed

11. Jørgensen R, Merrill AR, Andersen GR. The life and death of translation elongation factor 2. Biochem Soc Trans. 2006; 34(Pt 1), 1–6 PubMed

10. Yates SP, Jørgensen R, Andersen GR, Merrill AR. Stealth and mimicry by deadly bacterial toxins. Trends Biochem Sci. 2006; 31(2), 123-133 PubMed

9. Jørgensen R, Merrill AR, Yates SP, Marquez VE, Schwan AL, Boesen T, Andersen GR. Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry. Nature. 2005; 436(7053), 979-984 PubMed

8. Jørgensen R, Merrill AR, Yates SP, Marquez V, Schwann AL, Boesen T, Andersen GR. Revealing the deadly secrets of bacteria. In: BESSY Highlights 2005 (2006). Report chapter

7. Yates SP, Taylor PL, Jørgensen R, Ferraris D, Zhang J, Andersen GR, Merrill AR. Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa. Biochem J. 2005; 385(Pt 3), 667-675 PubMed

6. Spahn CM, Gomez-Lorenzo MG, Grassucci RA, Jørgensen R, Andersen GR, Beckmann R, Penczek PA, Ballesta JP, Frank J. Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. EMBO J. 2004; 23(5), 1008-1019 PubMed

5. Jørgensen R, Ortiz PA, Carr-Schmid A, Nissen P, Kinzy TG, Andersen GR. Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase. Nat Struct Biol. 2003; 10(5), 379-385 PubMed

4. Jørgensen R, Carr-Schmid A, Ortiz PA, Kinzy TG, Andersen GR. Purification and crystallization of the yeast elongation factor eEF2. Acta Crystallogr D Biol Crystallogr 2002; 58(Pt 4), 712-715 PubMed

3. Jørgensen R, Søgaard M, Rossing AB, Martensen PM, Justesen J. Identification and characterization of human mitochondrial tryptophanyl-tRNA synthetase. J Biol Chem. 2000; 275(22), 16820-16826 PubMed

2. Hansen LL, Jørgensen R, Justesen J. Assignment of the human mitochondrial translational release factor 1 (MTRF1) to chromosome 13q14.1-->q14.3 and of the human mitochondrial ribosome recycling factor (MRRF) to chromosome 9q32-->q34.1 with radiation hybrid mapping. Cytogenet Cell Genet. 2000; 88(1-2), 91-92 PubMed

1. Hartmann R, Olsen HS, Widder S, Jørgensen R, Justesen J. p59OASL, a 2'-5' oligoadenylate synthetase like protein: a novel human gene related to the 2'-5' oligoadenylate synthetase family. Nucleic Acids Res. 1998; 26(18), 4121-4128 PubMed

Last revised 15 November 2016